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Responses of the human brain to mild de- and rehydration explored in vivo by 1H-MR imaging and spectroscopy.
A.Biller, et al..
American Journal of Neuroradiology 36:2277-2284, 2015.
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This is the first study simultaneously evaluating changes in brain tissue fluid, metabolites, volume, and cortical thickness. Our results reflect cellular volume regulatory mechanisms at a macroscopic level and emphasize that it is essential to control for hydration levels in studies on brain morphometry and metabolism in order to avoid confounding the findings.
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