MIT
MGH
HMS
LCLN

LABORATORY FOR COMPUTATIONAL LONGITUDINAL NEUROIMAGING (LCLN)

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Research

Interdisciplinarity is what drives modern research...

Research Domains
  • Medical Image Computing, Computational NeuroImaging, Big Data Analysis,

  • Machine Learning, Computer Vision and Graphics, Computational Statistics,

  • Differential and Computational Geometry, Computational Topology,

  • Human Computer Interaction, Geometric Modeling, Computer-aided Design

Research Directions
In close collaboration with clinical and industrial partners, we develop advanced computational techniques for the analysis of large biomedical image datasets, including:
  • Development of innovative methods for reliable image acquisition, processing, analysis and interpretation – in particular sensitive longitudinal analysis, registration, reconstruction, segmentation and predictive modeling.
  • Machine learning, computer vision and statistical modeling for the extraction of biomarkers and other clinically relevant information from large data sets (big data) – in particular for computer-aided diagnosis (at presymptomatic stages) and prognosis, personalized medicine, treatment planning, patient stratification, and identification of risk- or preserving factors of neurodegenerative disease.
  • Our research focuses on improving our understanding of brain development, neurodegeneration (aging, dementia, Alzheimer's disease, Huntington's disease), the sensitive quantification of subtle drug effects, and improving tumor treatment assessment, via multi-modal imaging.
Methodology
Applications
brainshapes
Structural Brain Imaging
tractography
The Human Connectome
neurodegen2
Neurodegeneration and Disease
tumor
Tumor Treatment Assessment
caddementia
Computer-aided Diagnosis / Prognosis
drugefficacy
Drug Research and Personalized Medicine
histology
Histology / Validation
oct
Optical Coherence Tomography
brainprint
Neuroanatomical Biometrics
genetics
Genetics and Heritability
You can find out more about our research by reviewing our publications and software.
Research Funding
  • National Institutes of Health (NCI, NIBIB, ...)
  • Harvard NeuroDiscovery Center
  • Massachusetts Alzheimer's Disease Research Program
  • Genentech Foundation
  • NVIDIA
  • Alexander von Humboldt Foundation
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Martin Reuter - MIT - Cambridge, MA, USA - EMail: reu...@mit.edu
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